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Here's everything you need to know about this key AFC South matchup
The Panthers square off against a familiar NFC South adversary in their home opener
New Orleans and Seattle have new signal callers under center
The Colts aim to keep their unbeaten start going in a divisional matchup
Undefeated Tampa Bay looks to hold off winless New York
Los Angeles will try to win its third-straight against an AFC West opponent
It's the renewal of an old rivalry, but with a bunch of new faces
Arizona will visit San Francisco, and the winner will move to 3-0
It'll be another battle of the backup quarterbacks
Green Bay has looked like the NFL's best team through the first two weeks
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Let's preview and predict Sunday night's showdown